Enrofloxacin 2.27% Injection Enrofloxacin Antibacterial Injectable Solution 2.27% is indicated for the management of diseases in dogs associated with bacteria susceptible to enrofloxacin. It is useful for the treatment of infections such as: urinary tract infections, respiratory tract infections, and dermal infections. Fluroquinolone antibiotics interfere with bacterial DNA metabolism killing the bacteria. Enrofloxacin is bactericidal against a wide range of gram positive and gram negative bacteria. For Use in Dogs Only Use: Weight of Animal Enrofloxacin Injectable Solution 2.5 mg/kg 9.1 kg (20 lb) 1.00 ml 27.2 kg (60 lb) 3.00 ml Precautions: Keep out of reach of children. Do not use in pregnant or nursing animals. Enrofloxacin is contraindicated in dogs known to be hypersensitive to quinolones. Based on the studies discussed under the section on Animal Safety Summary, the use of enrofloxacin is contraindicated in small and medium breeds of dogs during the rapid growth phase (between 2 and 8 months of age). The safe use of enrofloxacin has not been established in large and giant breeds during the rapid growth phase. Large breeds may be in this phase for up to one year of age and the giant breeds for up to 18 months. In clinical field trials utilizing a daily oral dose of 5.0 mg/kg, there were no reports of lameness or joint problems in any breed. However, controlled studies with histological examination of the articular cartilage have not been conducted in the large or giant breeds. Store at controlled room temperature 68-77°F (20-25°C). Protect from direct sunlight. Do not freeze.