Nobivac Lyme the first vaccine licensed to aid in the prevention of subclinical arthritis and other signs of Lyme disease. The vaccine contains a traditional isolate targeted at OspA and a unique isolate proven to induce high levels of Borreliacideal antibodies to OspC1,2 Lyme vaccine designed to target the 2 key outer surface proteins (Osps) involved in disease transmission for a full level of protection. Proven to induce borreliacidal antibodies that bind to OspA and OspC, forming a complex that attacks the cell membrane and kills Borrelia burgdorferi. 1,2 Proven to help prevent clinical disease such as arthritis.2 Highly effective: no serologic evidence of exposure to Borrelia burgdorferi.2 All vaccines are shipped Express 1-2 Days. A $29.95 flat rate fee is charged for all orders containing vaccines. Someone should be present to sign for and receive the vaccine order when it ships to you. For more shipping info click here. NOTE: This item cannot be shipped to Minnesota, Canada and P.O. Boxes. Use must be approved by your veterinarian.