Equine Potomavac + IMRAB is for vaccinating horses against disease caused by rabies virus and aids in the prevention of disease in horses caused by Potomac horse fever (equine monocytic ehrlichiosis) caused by Ehrlichia risticii. This highly effective combination vaccine contains inactivated E. risticii combined with inactivated rabies virus to help protect your horse against Potomac horse fever which can lead to fever, colic, watery diarrhea and abortion, and rabies, a nervous system infection which is invariably fatal once symptoms develop. Equine Potomavac + IMRAB is a killed vaccine safe for intramuscular administration in healthy horses and foals at least 3 months of age. Unvaccinated horses will require a primary two-dose vaccination, three to four weeks apart. Annual revaccination is recommended. No reconstitution required. Equine combination vaccine For use in healthy horses and foals 3 months of age and older Protects against rabies virus and Potomac horse fever Killed virus vaccine, no mixing required Contains inactivated rabies virus All vaccines are shipped Express 1-2 Days. A $29.95 flat rate fee is charged for all orders containing vaccines. Someone should be present to sign for and receive the vaccine order when it ships to you. For more shipping info click here. NOTE: This item cannot be shipped to Minnesota, Canada and P.O. Boxes. Use must be approved by your veterinarian.