BioCalm Shampoo is a soothing soap-free shampoo for relief of itching in dogs, cats and horses. Formulated with 1% Pramoxine, MicroSilver BG and Ceramide III. 1% Pramoxine Hydrochloride acts as an effective topical agent to aid in alleviating itching and discomfort. Colloidal Oatmeal moisturizes and soothes itchy skin and helps to relieve symptoms of allergies, dry skin, hot spots, and flea dermatitis. Colloidal oatmeal shampoo also helps clean and soften the hair coat.