Zycortal Suspension 4ml

Zycortal Suspension 4ml

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Zycortal Suspension 4ml Zycortal Suspension (Desoxycorticosterone Pivalate) is an injectable for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison's Disease). Desoxycorticosterone is a corticosteroid with primarily mineralocorticoid activity, similar to aldosterone. In the kidney, desoxycorticosterone causes sodium and chloride ion retention, and hydrogen and potassium ion excretion, creating an osmotic gradient that promotes water absorption from the renal tubules. This increases extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output. Dispensed in: 25 mg/ml, 4 ml vial For Use in: Dogs only Side Effects: It has been demonstrated that Desoxycorticosterone Pivalate Injectable Suspension is well tolerated with a low incidence of side effects. In a small percentage of treated dogs, depression, excessive thirst and urination, digestive, skin and coat changes, weakness, and injection site reactions (pain, abscesses) may occur. Some of these effects may resolve with adjustments in dose or interval or concomitant glucocorticoid administration. Do not use in pregnant dogs or in dogs that are suffering from congestive heart disease, severe renal disease, or edema. Precautions: Do not use Zycortal Suspension in dogs that have previously had a hypersensitivity reaction to desoxycorticosterone pivalate. CAUTIONS: Any dog presenting with severe hypovolemia, dehydration, pre-renal azotemia and inadequate tissue perfusion ("Addisonian crisis") must be rehydrated with intravenous fluid (saline) therapy before starting treatment with Zycortal Suspension. Avoid inadvertent intravenous injection which may have an adverse effect on the dog. The effectivenes

Sku 012VED-38204


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